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Level 207

SN2 vs E2 Solvent


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Ignore?
I?
good leaving group
Br?
good leaving group
E2
1° Carbon (Strong Base, Hindered)
Cl?
good leaving group
?C///N
SN2
SN2
?:CN
SN2: substituted alkyl halides
methyl>1°>2°>3° [almost never!! it's too slow]
3°>2°>1° no methyl!!!!!!
E2 substituted alkyl halides
SH?
SN2
OH?
both
EtO?
both
MeO?
both
H2O
Bent (or) Angular
beta branching; steric hindrance!
SN2 isn't preferred when there is a lot of _______
diisopropylamine
E2
Triethylamine
E2
RS?
good nucleophile
H2S
SN2
RSH
SN2
H?
E2
DBN
E2
DBU
E2
MeOH
neither, its weak; SN1 or E1
EtOH
neither, its weak; SN1 or E1