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Disorders of haemostasis


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immune thrombocytopenic purpura
A disorder caused by anti-platelet antibodies
heparin-induced thrombocytopenia
A disorder caused by an immune reaction to the heparin-PF4 complex
haemophilia A
deficiency of Factor VIII that impairs the control of coagulation
haemophilia B
deficiency of Factor IX that impairs the control of coagulation
aPTT
The coagulation test that is prolonged in haemophilia
inhibitors
The biggest current issue with haemophilia treatment is the development of...
Christmas disease
An alternative name for haemophilia B
von Willebrand's disease
A disorder caused by an abnormality of vWF
ristocetin
In vWD, there is decreased activity with this co-factor
desmopressin
Treatment for vWD which causes release of vWF & factor VIII from endothelial cells
severe liver disease
A disorder that causes deficient synthesis of all clotting factors except VIII
INR
The coagulation test that is prolonged in vitamin K deficiency
D-dimer
Levels of this biomarker are measured to test for increased fibrinolysis