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Level 13

Malaria


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Plasmodium
Genus of parasites that cause human malaria
P.falciparum
Most common and most lethal species of Plasmodium
P.vivax
The only species of Plasmodium that is rare in Africa
P.malariae
A species of Plasmodium that tends to cause chills and fever every 3 days
P.ovale
A species of Plasmodium found almost exclusively in Africa that tends to cause chills and fever every 2 days
P.knowlesi
A new species of Plasmodium isolated from primates in Malaysia, potentially fatal to humans
Anopheles
Genus of mosquito that transmits all the Plasmodium species that cause malaria in humans
schizogony
Cell division where the nucleus divides several times before the cytoplasm separates, producing many cells
sporozite
Stage of Plasmodium spp. that enters the blood via mosquito bite
schizont
Stage of Plasmodium spp. that contains merozoites produced through schizogony
merozoite
Stage of Plasmodium spp. that infects red blood cells
trophozite
Stage of Plasmodium spp. within the red blood cell, before schizogony
gametocyte
Stage of Plasmodium spp. that is ingested by the mosquito
ookinete
Stage of Plasmodium spp. that is produced by the fusion of male & female gametocytes
oocyst
Stage of Plasmodium spp. that migrates to the mosquito salivary gland
hypnozoite
Stage of P.ovale & P.vivax that can remain dormant in the liver & cause relapse
mosquirix
New malaria vaccine that shows modest efficacy
chloroquine
Standard antimalarial that some strains of P.falciparum are resistant to
artermether
Antimalarial for the treatment of multi-drug resistant strains of P.falciparum