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Out damned spot, out!
Lady Macbeth tries to wash the imaginary blood off her hands. This symbolises her guilt and her deteriorating mental state
The Thane of wife has a wife....where is she now?
Lady Macbeth is confused and uncertain. This shows how she has been driven mad by guilt.
To bed, to bed! There's knocking at the gate.
In a hallucinatory state, Lady Macbeth is reliving Duncan's murder from earlier in the play.
If thou couldst, Doctor, cast the water of my land, find her disease and purge it to a pristine health
Macbeth implies that Scotland is suffering from a disease, which is ironic because HE is the disease.
Tomorrow and tomorrow and tomorrow/ Out! Out brief candle!
Macbeth sounds cynical and weary after hearing his wife has died. He thinks life is meaningless.
Turn, hell-hound, turn!
Macduff vows to kill Macbeth and get revenge for his slaughtered family
Macduff was from his mother's womb untimely ripped
Macduff reveals he was born by caesarian section, meaning that he is the one who will 'harm' Macbeth