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*Herhaling: blood lipoproteins


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Chylomicrons
have a diameter ranging from 0.03 – 0.5μm. They are produced by epithelial cells in the intestine. The triglyceride/cholesterol ratio is 10:1.
Chylomicrons
composed of: mainly apoA-I, apoB, apoC, and apoE. Carry absorbed lipids from the intestinal tract to the blood stream.
Very low-density lipoproteins (VLDL)
have a diameter ranging from 25 – 75nm. They contain mostly triglycerides manufactured by the liver plus small amounts of phospholipids and cholesterol. The triglyceride/cholesterol ratio is 5:1.
Very low-density lipoproteins (VLDL)
built up of apoB, apoC and apoE. produced in the liver and responsible for the transport of triglycerides to peripheral tissues.
Intermediate-density lipoproteins
intermediate in size and lipid composition between VLDLs and low-density lipoproteins (LDLs). contain smaller amounts of triglycerides than do VLDLs and an increasing concentration of cholesterol. The triglyceride/cholesterol ratio is 1:1.
Intermediate-density lipoproteins
contain apoproteins apoB, apoC and apoE.
Low-density lipoproteins (LDL)
are composed of large amounts of cholesterol and lesser phospholipids.measure about 25 nm in diameter. Their major protein content is formed by apoB. The main functionis to deliver cholesterol to peripheral tissues. Because of their role in arterial plaques, they are often called "bad cholesterol".
High-density lipoproteins (HDL)
are the smallest of the lipoproteins with a diameter of 10 nm. They contain equal amounts of protein and lipid (mainly cholesterol and phospholipids). produced by the intestine, liver and in the plasma. Function is to transport excess cholesterol from the peripheral tissue back to the liver for storage or excretion in bile. Since it returns cholesterol from peripheral tissues and will not cause vascular problems, it is called the "good cholesterol".
High-density lipoproteins (HDL)
its significant apoproteins are mainly apoA and small amounts of apoC and apoE.